Welcome to SENTINUS Trial
This UK study aims to train imaging specialists to perform a contrast ultrasound test to find and biopsy armpit sentinel lymph nodes in patients with breast cancer and assess how effective the test is at finding cancerous deposits (metastases)Welcome to Sentinus Trial
This UK study aims to train imaging specialists to perform a contrast ultrasound test to find and biopsy armpit sentinel lymph nodes in patients with breast cancer and assess how effective the test is at finding cancerous deposits (metastases)Introduction
Around 46,000 people are diagnosed with invasive breast cancer every year in the UK. As well as removing the tumour in the breast, they are advised to have some or all of their lymph nodes removed from the armpit. As most patients have early stage breast cancer, about 70% will not have cancer deposits in the lymph nodes. Therefore, many patients risk the potential complications from armpit surgery such as infection and arm swelling (ymphoedema), for no benefit. There is already a lot of effort to reduce armpit surgery and better use of ultrasound may help to identify patients who don’t need this surgery at all.
Navigating this site
All study documents, including the Participant Information Sheet and Consent form, and those required by R&D departments and pharmacists, can be downloaded from the For Site Staff area of the site.
Introduction
Around 46,000 people are diagnosed with invasive breast cancer every year in the UK. As well as removing the tumour in the breast, they are advised to have some or all of their lymph nodes removed from the armpit. As most patients have early stage breast cancer, about 70% will not have cancer deposits in the lymph nodes. Therefore, many patients risk the potential complications from armpit surgery such as infection and arm swelling (lymphoedema), for no benefit. There is already a lot of effort to reduce armpit surgery and better use of ultrasound may help to identify patients who don’t need this surgery at all.
Navigating this site
All study documents, including the Participant Information Sheet and Consent form, and those required by R&D departments and pharmacists, can be downloaded from the For Site Staff area of the site.